Principal Investigator

Lisa Rotenstein, MD, MBA

Division of General Internal Medicine
Medical Director for Population Health
Assistant Professor of Medicine, Harvard Medical School

Dr. Rotenstein is a primary care physician, researcher, and operational leader. She is also an Assistant Professor at Harvard Medical School and serves as affiliate faculty at Ariadne Labs and the Harvard Center for Primary Care. Her areas of scholarly focus are related to primary care design, the electronic health record (EHR), physician experience, and gender issues in medicine. Dr. Rotenstein is nationally recognized expert in clinician wellbeing and the impact of the EHR on clinicians. She has 56 peer reviewed publications (including two with over 1,000 citations and in top journals such as JAMA, NEJM, JAMA Internal Medicine, Annals of Internal Medicine) and has been invited to present her work across the United States, including to the National Academy of Medicine.  

Additionally, Dr. Rotenstein serves as Medical Director for Population Health for the Brigham and Women’s Hospital Primary Care Center of Excellence. In this position, she is responsible for ambulatory quality metrics, population health, and integrated behavioral health for Brigham and Women’s Hospital’s 16 primary care practices and 175,000 primary care patients.



David Bates, MD

Division of General Internal Medicine
Chief, General Internal Medicine and Primary Care
Professor of Medicine, Harvard Medical School

Dr. Bates is an internationally recognized expert in patient safety, evaluation, clinical informatics, and medication safety, and has done extensive work on improving efficiency and quality, and on assessing health information technology (IT) adoption. He has expertise in creating novel methods and IT tools to promote patient-centered care and patient engagement, and to facilitate interdisciplinary communication and collaboration. He leads various research projects related to health IT and patient engagement and experience, including integrated tools that enhance interdisciplinary communication and collaboration while incorporating patient engagement. Dr. Bates is in the final stages of a 4-year AHRQ P30 center grant to create a Patient Safety Learning Laboratory (PSLL) to develop IT tools to engage patients and providers in reliable identification, assessment, and reduction of patient safety threats in real-time in the hospital setting. He is focused on patient safety and informatics research with the goal of improving the quality and safety of patient care. He led much of the original work demonstrating the effects of implementation of computerized physician order entry on medication safety and am a leader in advancing patient engagement with health IT solutions to improve the quality and safety of health care, as well as IT systems. In addition, Dr. Bates is the Past President of the International Society of Quality in Healthcare and am past Chair of the Board of Directors of the American Medical Informatics Association

Staff Members

Christine Iannaccone, MPH

Sr. Project Manager

Research Interests

Christine is a senior project manager at Brigham and Women’s Hospital in the Division of General Internal Medicine. She has expertise in running large-scale clinical projects spanning several research areas, including cohort studies and large data repositories. She has experience conducting clinical and information technology-related research studies, including quantitative, qualitative, and survey-based research. In addition, Christine’s work experience includes managing multi-site research projects, developing research proposals and budgets, and managing IRB protocol submissions.

Michelle Frits

Sr. Data Analyst

Research Interests

Michelle is a statistical programmer, database analyst/builder, and user interface designer with over 20 years of experience. After earning business and quantitative methods/computer science degrees, she worked in the insurance and financial industries before matriculating to healthcare research. She has extensive experience in multiple programming languages and has worked with clinical and other data from various sources. She oversaw all aspects of data collection, management, and analysis for a longitudinal clinical registry for patients with rheumatoid arthritis before switching her focus to patient safety. Since then, Michelle has helped conduct a significant patient safety research project where she worked with 14 institutions across Massachusetts to collect and harmonize electronic health records (EHR) data from 6 different EHR systems. She then designed, implemented, and supervised all aspects of a data entry system before combining and analyzing all data. As part of a project to ensure patients receive appropriate follow-up care, Michelle developed a robust database tracking and reporting system, again aggregating data from disparate data files while working on process improvement.